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Showing posts with label San Diego. Show all posts
Showing posts with label San Diego. Show all posts

Sunday, November 1, 2009

Chronic Spinal Cord Injury


Scientists at the University of California, San Diego School of Medicine report that regeneration of central nervous system axons can be achieved in rats even when treatment delayed is more than a year after the original spinal cord injury.

Mark Tuszynski, MD, PhD. (Credit: Image courtesy of University of California - San Diego)

"The good news is that when axons have been cut due to spinal cord injury, they can be coaxed to regenerate if a combination of treatments is applied," said lead author Mark Tuszynski, MD, PhD, professor of neurosciences and director of the Center for Neural Repair at UC San Diego, and neurologist at the Veterans Affairs San Diego Health System. "The chronically injured axon is not dead."

Saturday, October 17, 2009

Scientists Discover Protein Receptor For Carbonation Taste


In 1767, chemist Joseph Priestley stood in his laboratory one day with an idea to help English mariners stay healthy on long ocean voyages. He infused water with carbon dioxide to create an effervescent liquid that mimicked the finest mineral waters consumed at European health spas. Priestley's man-made tonic, which he urged his benefactors to test aboard His Majesty's ships, never prevented a scurvy outbreak. But, as the decades passed, his carbonated water became popular in cities and towns for its enjoyable taste and later as the main ingredient of sodas, sparkling wines, and all variety of carbonated drinks.

 Sparkling water. (Credit: iStockphoto/Jesus Ayala)

Missing from this nearly 250-year-old story is a scientific explanation of how people taste the carbonation bubbling in their glass. In this week's issue of the journal Science, researchers at the National Institute of Dental and Craniofacial Research (NIDCR), part of the National Institutes of Health, and their colleagues from the Howard Hughes Medical Institute at the University of California, San Diego (UCSD) report that they have discovered the answer in mice, whose sense of taste closely resembles that of humans.

Tuesday, September 29, 2009

Discovery Brings New Type Of Fast Computers Closer To Reality


Physicists at UC San Diego have successfully created speedy integrated circuits with particles called “excitons” that operate at commercially cold temperatures, bringing the possibility of a new type of extremely fast computer based on excitons closer to reality.

Alex High and Aaron Hammack adjust the optics in their UCSD lab. (Credit: Image courtesy of University of California - San Diego)

  
Their discovery, detailed this week in the advance online issue of the journal Nature Photonics, follows the team’s demonstration last summer of an integrated circuit—an assembly of transistors that is the building block for all electronic devices—capable of working at 1.5 degrees Kelvin above absolute zero. That temperature, equivalent to minus 457 degrees Fahrenheit, is not only less than the average temperature of deep space, but achievable only in special research laboratories.

Friday, September 4, 2009

Believing Is Seeing: Thoughts Color Perception -- Implications From Everyday Misunderstandings To Eyewitness Memory


Folk wisdom usually has it that "seeing is believing," but new research suggests that "believing is seeing," too – at least when it comes to perceiving other people's emotions.

Researchers showed experimental participants still photographs of faces computer-morphed to express ambiguous emotion and instructed them to think of these faces as either angry or happy. Once an ambiguous look was interpreted, it biased subsequent perception. (Credit: Courtesy of Piotr Winkielman, UC San Diego)

An international team of psychologists from the United States, New Zealand and France has found that the way we initially think about the emotions of others biases our subsequent perception (and memory) of their facial expressions. So once we interpret an ambiguous or neutral look as angry or happy, we later remember and actually see it as such.


The study, published in the September issue of the journal Psychological Science, "addresses the age-old question: 'Do we see reality as it is, or is what we see influenced by our preconceptions?'" said coauthor Piotr Winkielman, professor of psychology at the University of California, San Diego. "Our findings indicate that what we think has a noticeable effect on our perceptions."


"We imagine our emotional expressions as unambiguous ways of communicating how we're feeling," said coauthor Jamin Halberstadt, of the University of Otago in New Zealand, "but in real social interactions, facial expressions are blends of multiple emotions – they are open to interpretation. This means that two people can have different recollections about the same emotional episode, yet both be correct about what they 'saw.' So when my wife remembers my smirk as cynicism, she is right: her explanation of the expression at the time biased her perception of it. But it is also true that, had she explained my expression as empathy, I wouldn't be sleeping on the couch."


"It's a paradox," Halberstadt added. "The more we seek meaning in other emotions, the less accurate we are in remembering them."


The researchers point out that implications of the results go beyond everyday interpersonal misunderstandings – especially for those who have persistent or dysfunctional ways of understanding emotions, such as socially anxious or traumatized individuals. For example, the socially anxious have negative interpretations of others' reactions that may permanently color their perceptions of feelings and intentions, perpetuating their erroneous beliefs even in the face of evidence to the contrary. Other applications of the findings include eyewitness memory: A witness to a violent crime, for example, may attribute malice to a perpetrator – an impression which, according to the researchers, will influence memory for the perpetrator's face and emotional expression.


The researchers showed experimental participants still photographs of faces computer-morphed to express ambiguous emotion and instructed them to think of these faces as either angry or happy. Participants then watched movies of the faces slowly changing expression, from angry to happy, and were asked to find the photograph they had originally seen. People's initial interpretations influenced their memories: Faces initially interpreted as angry were remembered as expressing more anger than faces initially interpreted as happy.


Even more interesting, the ambiguous faces were also perceived and reacted to differently. By measuring subtle electrical signals coming from the muscles that control facial expressions, the researchers discovered that the participants imitated – on their own faces – the previously interpreted emotion when viewing the ambiguous faces again. In other words, when viewing a facial expression they had once thought about as angry, people expressed more anger themselves than did people viewing the same face if they had initially interpreted it as happy.


Because it is largely automatic, the researchers write, such facial mimicry reflects how the ambiguous face is perceived, revealing that participants were literally seeing different expressions.


"The novel finding here," said Winkielman, of UC San Diego, "is that our body is the interface: The place where thoughts and perceptions meet. It supports a growing area of research on 'embodied cognition' and 'embodied emotion.' Our corporeal self is intimately intertwined with how – and what – we think and feel."


Also coauthors on the study are Paula Niedenthal and Nathalie Dalle, both at the Universite Blaise Pascall, Clermont-Ferrand, France.


The research was supported by a National Science Foundation grant to Winkielman and Niedenthal and a University of Otago Research Grant to Halberstadt.



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