Following Genetic Footprints out of Africa: First Modern Humans Settled in Arabia

Following Genetic Footprints out of Africa: First Modern Humans Settled in Arabia

  9:18:00 PM    Science Lover

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A new study, using genetic analysis to look for clues about human migration over sixty thousand years ago, suggests that the first modern humans settled in Arabia on their way from the Horn of Africa to the rest of the world.

A new study, using genetic analysis to 
look for clues about human migration 
over sixty thousand years ago, suggests 
that the first modern humans settled in 
Arabia on their way from the Horn of 
Africa to the rest of the world. 
(Credit: © photoromano / Fotolia)

Led by the University of Leeds and the University of Porto in Portugal, the study is recently published in American Journal of Human Genetics and provides intriguing insight into the earliest stages of modern human migration, say the researchers.

"A major unanswered question regarding the dispersal of modern humans around the world concerns the geographical site of the first steps out of Africa," explains Dr Luísa Pereira from the Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP). "One popular model predicts that the early stages of the dispersal took place across the Red Sea to southern Arabia, but direct genetic evidence has been thin on the ground."

The international research team, which included colleagues from across Europe, Arabia and North Africa, analysed three of the earliest non-African maternal lineages. These early branches are associated with the time period when modern humans first successfully moved out of Africa.

Using mitochondrial DNA analysis, which traces the female line of descent and is useful for comparing relatedness between different populations, the researchers compared complete genomes from Arabia and the Near East with a database of hundreds more samples from Europe. They found evidence for an ancient ancestry within Arabia.

Professor Martin Richards of the University of Leeds' Faculty of Biological Sciences, said: "The timing and pattern of the migration of early modern humans has been a source of much debate and research. Our new results suggest that Arabia, rather than North Africa or the Near East, was the first staging-post in the spread of modern humans around the world."

The research was funded by the Portuguese Foundation for Science and Technology, the Leverhulme Trust, and the DeLaszlo Foundation.

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'Plasmobot': Scientists To Design First Robot Using Mould

'Plasmobot': Scientists To Design First Robot Using Mould

  10:23:00 PM    Science Lover

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Scientists at the University of the West of England are to design the first ever biological robot using mould.

Plasmodium used in the research.
(Credit: Image courtesy of University of the West of England)

Researchers have received a Leverhulme Trust grant worth £228,000 to develop the amorphous non-silicon biological robot, plasmobot, using plasmodium, the vegetative stage of the slime mould Physarum polycephalum, a commonly occurring mould which lives in forests, gardens and most damp places in the UK. The Leverhulme Trust funded research project aims to design the first every fully biological (no silicon components) amorphous massively-parallel robot.

This project is at the forefront of research into unconventional computing. Professor Andy Adamatzky, who is leading the project, says their previous research has already proved the ability of the mould to have computational abilities.

Professor Adamatzky explains, “Most people’s idea of a computer is a piece of hardware with software designed to carry out specific tasks. This mould, or plasmodium, is a naturally occurring substance with its own embedded intelligence. It propagates and searches for sources of nutrients and when it finds such sources it branches out in a series of veins of protoplasm. The plasmodium is capable of solving complex computational tasks, such as the shortest path between points and other logical calculations. Through previous experiments we have already demonstrated the ability of this mould to transport objects. By feeding it oat flakes, it grows tubes which oscillate and make it move in a certain direction carrying objects with it. We can also use light or chemical stimuli to make it grow in a certain direction.

“This new plasmodium robot, called plasmobot, will sense objects, span them in the shortest and best way possible, and transport tiny objects along pre-programmed directions. The robots will have parallel inputs and outputs, a network of sensors and the number crunching power of super computers. The plasmobot will be controlled by spatial gradients of light, electro-magnetic fields and the characteristics of the substrate on which it is placed. It will be a fully controllable and programmable amorphous intelligent robot with an embedded massively parallel computer.”

This research will lay the groundwork for further investigations into the ways in which this mould can be harnessed for its powerful computational abilities.

Professor Adamatzky says that there are long term potential benefits from harnessing this power, “We are at the very early stages of our understanding of how the potential of the plasmodium can be applied, but in years to come we may be able to use the ability of the mould for example to deliver a small quantity of a chemical substance to a target, using light to help to propel it, or the movement could be used to help assemble micro-components of machines. In the very distant future we may be able to harness the power of plasmodia within the human body, for example to enable drugs to be delivered to certain parts of the human body. It might also be possible for thousands of tiny computers made of plasmodia to live on our skin and carry out routine tasks freeing up our brain for other things. Many scientists see this as a potential development of amorphous computing, but it is purely theoretical at the moment.”

Professor Adamatzky has recently edited and had published by Springer, ‘Artificial Life Models in Hardware’ aimed at students and researchers of robotics. The book focuses on the design and real-world implementation of artificial life robotic devices and covers a range of hopping, climbing, swimming robots, neural networks and slime mould and chemical brains.

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